Leonbergers LPN1 genetic test results

 

Three different types of results are available.

Clear (N/N) The dog is clear of the LPN1 gene mutation. This means that the dog has two copies of the normal gene (this is also referred to as being homozygous normal). Clear dogs cannot pass the LPN1 gene mutation to their offspring.

At risk (D/N) The dog has one copy of the normal form of the gene and one copy of the mutated form of the LPN1 gene (this is also referred to as being heterozygous) and is known as a carrier.  LPN1 at risk dogs will, on average, pass the LPN1 gene mutation on to half of their offspring.

Affected (D/D) The dog has two copies of the LPN1 gene mutation (this is also referred to as being homozygous affected).  A dog with two copies of the LPN1 gene mutation will develop this form of Leonberger polyneuropathy.  Affected dogs will pass one copy of this mutation on to all of their offspring.

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